BDBM144495 US8969568, 47::US8969568, 52::US8969568, 78

SMILES COc1ccc(cc1OC)-c1cc2ncccc2c(OC[C@H]2CNC(=O)C2)n1

InChI Key InChIKey=YSFVSZHFOYRRJX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 144495   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144495(US8969568, 52 | US8969568, 78 | US8969568, 47)
Affinity DataIC50: 0.900nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144495(US8969568, 52 | US8969568, 78 | US8969568, 47)
Affinity DataIC50: 4.10nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharma

US Patent
LigandPNGBDBM144495(US8969568, 52 | US8969568, 78 | US8969568, 47)
Affinity DataIC50: 10.7nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
US Patent