BDBM14528 2-[6-(3-aminophenyl)-5-chloro-3-(ethylamino)-2-oxo-1,2-dihydropyrazin-1-yl]-N-[(4-carbamimidoylphenyl)methyl]acetamide::Pyrazinone Analog 29b

SMILES CCNc1nc(Cl)c(-c2cccc(N)c2)n(CC(=O)NCc2ccc(cc2)C(N)=N)c1=O

InChI Key InChIKey=MLDYDFWLYIKPSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14528   

TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14528(2-[6-(3-aminophenyl)-5-chloro-3-(ethylamino)-2-oxo...)
Affinity DataIC50: 40nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14528(2-[6-(3-aminophenyl)-5-chloro-3-(ethylamino)-2-oxo...)
Affinity DataIC50: 2.84E+4nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed