BDBM14567 N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(3-chlorophenyl)-2-oxo-3-[(2-phenylethyl)amino]-1,2-dihydropyrazin-1-yl]acetamide::Pyrazinone Analog 31b

SMILES NC(=N)c1ccc(CNC(=O)Cn2c(c(Cl)nc(NCCc3ccccc3)c2=O)-c2cccc(Cl)c2)cc1

InChI Key InChIKey=SQESJORMSRXRJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14567   

TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14567(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(3...)
Affinity DataIC50: 720nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

LigandPNGBDBM14567(N-[(4-carbamimidoylphenyl)methyl]-2-[5-chloro-6-(3...)
Affinity DataIC50: 1.98E+3nMAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed