BDBM14601 CHEMBL125585::N-[(4-carbamimidoylphenyl)methyl]-2-[2-hydroxy-6-phenyl-3-(propan-2-ylamino)phenyl]acetamide::N-{4-[Amino(imino)methyl]benzyl}-2-[3-hydroxy-4-(isopropyl)-1,1-biphenyl-2-yl]acetamide::Substituted Benzene Analog 53

SMILES CC(C)Nc1ccc(-c2ccccc2)c(CC(=O)NCc2ccc(cc2)C(N)=N)c1O

InChI Key InChIKey=CTWGJCJJBKHITF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14601   

TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14601(N-{4-[Amino(imino)methyl]benzyl}-2-[3-hydroxy-4-(i...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14601(N-{4-[Amino(imino)methyl]benzyl}-2-[3-hydroxy-4-(i...)
Affinity DataIC50: 2.50E+3nMpH: 8.0 T: 2°CAssay Description:Recombinant human Factor VIIa and soluble tissue factor were added to a 96-well assay plate containing substrate and inhibitor in reaction buffer. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14601(N-{4-[Amino(imino)methyl]benzyl}-2-[3-hydroxy-4-(i...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human thrombin and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14601(N-{4-[Amino(imino)methyl]benzyl}-2-[3-hydroxy-4-(i...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14601(N-{4-[Amino(imino)methyl]benzyl}-2-[3-hydroxy-4-(i...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Human Factor Xa and substrate were added to a 96-well assay plate containing inhibitor in reaction buffer. The rate of hydrolysis of the substrate wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

LigandPNGBDBM14601(N-{4-[Amino(imino)methyl]benzyl}-2-[3-hydroxy-4-(i...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed