BDBM150224 US8980906, 26

SMILES NC(=O)C[C@H](NC(=O)c1cc2C[C@H]3[C@H]4Cc5ccc(O)cc5[C@@]3(CCN4CC3CC3)Cc2[nH]c1=O)C(N)=O

InChI Key InChIKey=RHAIHBNTVZYFBZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150224   

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM150224(US8980906, 26)
Affinity DataKi:  0.710nM ΔG°:  -13.5kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2015
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM150224(US8980906, 26)
Affinity DataKi:  0.860nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/10/2015
Entry Details
US Patent