BDBM150991 US8987257, 4

SMILES C[C@H]1COCCN1c1nc(nc2[nH]c(nc12)-c1ccc(F)c(CO)c1)N1CCOCC1

InChI Key InChIKey=CWQWCVCZQYDZSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 150991   

TargetSerine/threonine-protein kinase mTOR(Human)
Novartis

US Patent
LigandPNGBDBM150991(US8987257, 4)
Affinity DataIC50: 1.42E+3nMpH: 7.5 T: 2°CAssay Description:IC50s for mTOR interacting compounds were assessed using the FRAP1/mTOR TR-FRET tracer assay (Invitrogen by Life Technologies). FRAP1/mTOR (PV4753) a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

LigandPNGBDBM150991(US8987257, 4)
Affinity DataIC50: 1.80E+3nMpH: 7.5 T: 2°CAssay Description:PI3K KinaseGlo assay: 50 mL of compound dilutions were dispensed onto black 384-well low volume Non Binding Styrene (NBS) plates (Costar Cat. No. NBS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent