BDBM151514 US8987314, B325

SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(O)=O)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1

InChI Key InChIKey=FGYILSKPCFDTDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151514   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151514(US8987314, B325)
Affinity DataIC50: 1.20nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151514(US8987314, B325)
Affinity DataIC50: 104nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent