BDBM152289 US8993557, 33

SMILES Oc1c(ccn(CC(F)(F)F)c1=O)C(=O)NC1CCN(CC1)c1ccc(F)cc1

InChI Key InChIKey=HOQBIGXCMYBDET-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152289   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM152289(US8993557, 33)
Affinity DataIC50: 4.57E+3nMpH: 8.0Assay Description:Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
US Patent