BDBM152294 US8993557, 32

SMILES Cn1c(cc(C(=O)NCc2cccc(c2)-c2ccc(Cl)cc2)c(O)c1=O)C(F)(F)F

InChI Key InChIKey=HMZYUBJCQJIPAW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152294   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM152294(US8993557, 32)
Affinity DataIC50: 11.3nMpH: 8.0Assay Description:Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
US Patent