BDBM152640 4-(1,3-Dioxoisoindolin-2-yl)-N,N-diethyl benzenesulphonamide (3)::BDBM152641::BDBM152660

SMILES Brc1cccc(NC(=S)Nc2ccc(cc2)C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)c1

InChI Key InChIKey=RUVCMTGTEXZFNX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 152640   

TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

LigandPNGBDBM152640(BDBM152660 | 4-(1,3-Dioxoisoindolin-2-yl)-N,N-diet...)
Affinity DataIC50: 1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetGenome polyprotein(DENV-2)
Birla Institute of Technology

LigandPNGBDBM152640(BDBM152660 | 4-(1,3-Dioxoisoindolin-2-yl)-N,N-diet...)
Affinity DataIC50: 1.00E+5nMpH: 8.5Assay Description:To measure the inhibitory activities of the compounds, the DENV2 NS2B-NS3 protease activities were measured in the presence of the compounds using Bz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Bovine)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM152640(BDBM152660 | 4-(1,3-Dioxoisoindolin-2-yl)-N,N-diet...)
Affinity DataIC50: 1.31E+5nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed