BDBM152783 1-[(2,3,5-trimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride (3)

SMILES Cl.COc1ccccc1N1CCN(CCCOc2cc(C)cc(C)c2C)CC1

InChI Key InChIKey=HVKDOJPBIJUDIG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 152783   

Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

LigandPNGBDBM152783(1-[(2,3,5-trimethylphenoxy)propyl]-4-(2-methoxyphe...)
Affinity DataKi:  6nM ΔG°:  -11.2kcal/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

LigandPNGBDBM152783(1-[(2,3,5-trimethylphenoxy)propyl]-4-(2-methoxyphe...)
Affinity DataKi:  25nM ΔG°:  -10.4kcal/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

LigandPNGBDBM152783(1-[(2,3,5-trimethylphenoxy)propyl]-4-(2-methoxyphe...)
Affinity DataKi:  4.47E+3nM ΔG°:  -7.29kcal/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed