BDBM153109 US8993631, 16-8::US9006249, Example 3-60

SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1c[nH]c(n1)C(O)=O)C(O)=O

InChI Key InChIKey=ZGZOWIGWICXUAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153109   

TargetNeprilysin(Human)
Novartis

US Patent
LigandPNGBDBM153109(US8993631, 16-8 | US9006249, Example 3-60)
Affinity DataIC50: 7.30nMpH: 7.4 T: 2°CAssay Description:See A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7 Doering K, Meder G, Hinnenberger M, Woelcke J, Mayr L ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
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TargetMembrane metallo-endopeptidase-like 1(Human)
Novartis

US Patent
LigandPNGBDBM153109(US8993631, 16-8 | US9006249, Example 3-60)
Affinity DataIC50: 7.30nMpH: 7.4 T: 2°CAssay Description:Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
Go to US Patent