BDBM153533 BDBM153612::US8999975, 50

SMILES O[C@H]1C[C@H]2C[C@@H]1N[C@@H]2C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(C#N)c(F)c1)C#N

InChI Key InChIKey=ZMJPMXXVIHXCKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153533   

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM153533(US8999975, 50 | BDBM153612)
Affinity DataIC50: 13nMpH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM153533(US8999975, 50 | BDBM153612)
Affinity DataIC50: 14nMpH: 6.0 T: 2°CAssay Description:The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
US Patent