BDBM153853 US8999981, A122::US8999981, A98

SMILES C.C[C@H]1CN(CC2CC2)CCN1C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C

InChI Key InChIKey=FGZSNQATHSBBQL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153853   

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153853(US8999981, A98 | US8999981, A122)
Affinity DataKi:  13.3nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent

TargetProtein kinase C beta type(Human)
Pfizer

US Patent
LigandPNGBDBM153853(US8999981, A98 | US8999981, A122)
Affinity DataKi:  19.1nM ΔG°:  -10.7kcal/molepH: 7.4 T: 2°CAssay Description:Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
US Patent