BDBM15388 3-(5-chloro-2,4-dihydroxyphenyl)-N-(3-methoxyphenyl)-1H-pyrazole-4-carboxamide::3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamide 14c

SMILES COc1cccc(NC(=O)c2c[nH]nc2-c2cc(Cl)c(O)cc2O)c1

InChI Key InChIKey=OOHANKFAARLWQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15388   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15388(3-(5-chloro-2,4-dihydroxyphenyl)-N-(3-methoxypheny...)
Affinity DataIC50: 1.17E+4nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed