BDBM15397 3-(5-chloro-2,4-dihydroxyphenyl)-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide::3-(5-chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamide 14l

SMILES Oc1cc(O)c(cc1Cl)-c1n[nH]cc1C(=O)NCc1ccc(F)cc1

InChI Key InChIKey=KSQXYHCHSNPQNL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15397   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15397(3-(5-chloro-2,4-dihydroxyphenyl)-N-[(4-fluoropheny...)
Affinity DataIC50: 5.35E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed