BDBM15484 (+/-) racemate::(3R,4S)-4-(2,4-dichlorophenyl)-1-[5-(4-methoxyphenyl)pyrimidin-2-yl]pyrrolidin-3-amine::Pyrrolidine-constrained phenethylamine 18c

SMILES COc1ccc(cc1)-c1cnc(nc1)N1C[C@H](N)[C@H](C1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=MGPCIBLVBGADEC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15484   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15484((3R,4S)-4-(2,4-dichlorophenyl)-1-[5-(4-methoxyphen...)
Affinity DataKi:  430nM ΔG°:  -8.59kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2007
Entry Details Article
PubMed