BDBM154900 US8999957, Table 4, Compound 5

SMILES CN1C[C@@H](Cc2c(F)cccc2F)C[C@H](C1)NC(=O)c1ccc2[nH]nc(-c3ccc4nc(C)nn4c3)c2c1

InChI Key InChIKey=GWBPKQAQKLPXFW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 154900   

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 154900BDBM154900(US8999957, Table 4, Compound 5)
Affinity DataIC50: 1.45nMAssay Description:Condition 1: Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2015
Entry Details
US Patent