BDBM155385 US9006282, Example 3, Compound 4

SMILES CCCOC1C[C@H](O)C[C@@H](CCn2c(C(C)C)c(C(=O)Nc3ccccc3)c(c2-c2ccc(F)cc2)-c2ccccc2)O1

InChI Key InChIKey=QSPZJDGFFMSQPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155385   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Redx Pharma

US Patent
LigandPNGBDBM155385(US9006282, Example 3, Compound 4)
Affinity DataIC50: 1nMpH: 7.2Assay Description:All assays were carried out in a reaction buffer containing 100 nM KxPO4 at pH 7.2, 1 mM EDTA, 500 mM KCl and 1 mg/ml BSA. The concentrations of NADP...More data for this Ligand-Target Pair
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Date in BDB:
10/26/2015
Entry Details
US Patent