BDBM155972 US9018214, 23

SMILES C[C@@H]1CN(CC(=O)N2CC3(CCN(CC3)C(=O)OCc3ccccc3)c3ccc(Cl)cc23)CCN1

InChI Key InChIKey=SCDNUCIMDRNQQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 155972   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 155972BDBM155972(US9018214, 23)
Affinity DataIC50: 1.10E+4nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 155972BDBM155972(US9018214, 23)
Affinity DataIC50: 1.80E+4nMpH: 7.5 T: 2°CAssay Description:Modified SMAC peptides and compounds were tested for their ability to displace the fluorescent tracer from either XIAP, clAP-1 or clAP-2. BIR3 domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
US Patent