BDBM156419 US9023354, AD4-12906

SMILES Cc1ccnc(NC(c2cccc(Cl)c2Cl)c2ccc3cccnc3c2O)c1

InChI Key InChIKey=HQICAVDTVBACIN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 156419   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
TBA

US Patent
LigandPNGBDBM156419(US9023354, AD4-12906)
Affinity DataIC50: 4.40E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
TBA

US Patent
LigandPNGBDBM156419(US9023354, AD4-12906)
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein Mdm4(Human)
Yantai University

Curated by ChEMBL
LigandPNGBDBM156419(US9023354, AD4-12906)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity to MDMX (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed