BDBM156435 US10118915, Compound 229::US20250346584, Compound 229::US9682966, 229

SMILES Cc1noc(n1)-c1cc2ccc(C)cc2nc1N1CCC(NC2CCCCC2)C(CO)C1

InChI Key InChIKey=LWNRBYWDPUQWTE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 156435   

LigandChemical structure of BindingDB Monomer ID 156435BDBM156435(US9682966, 229 | US10118915, Compound 229 | US2025...)
Affinity DataIC50: 5nMAssay Description:The IC50 of each compound shown in Table was with respect to the kappa opioid receptor was determined. The cell line for the OPRK1 antagonist assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 156435BDBM156435(US9682966, 229 | US10118915, Compound 229 | US2025...)
Affinity DataIC50: 5nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 156435BDBM156435(US9682966, 229 | US10118915, Compound 229 | US2025...)
Affinity DataIC50: 5nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent