BDBM156526 US10118915, Compound 312::US20250346584, Compound 312::US9682966, 312

SMILES COC1CN(CCC1NC1CCCCCC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1

InChI Key InChIKey=XMWRBMGKVCIHKF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 156526   

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 156526BDBM156526(US9682966, 312 | US10118915, Compound 312 | US2025...)
Affinity DataIC50: 0.700nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 156526BDBM156526(US9682966, 312 | US10118915, Compound 312 | US2025...)
Affinity DataIC50: 0.700nMAssay Description:The IC50 of each compound shown in Table was with respect to the kappa opioid receptor was determined. The cell line for the OPRK1 antagonist assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2026
Entry Details

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 156526BDBM156526(US9682966, 312 | US10118915, Compound 312 | US2025...)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent