BDBM156544 US10118915, Compound 326::US20250346584, Compound 326::US9682966, 326

SMILES COC1CN(CCC1NC1CCOCC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1

InChI Key InChIKey=QPTLSLJLZSPXTO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 156544   

LigandChemical structure of BindingDB Monomer ID 156544BDBM156544(US9682966, 326 | US10118915, Compound 326 | US2025...)
Affinity DataIC50: 1.90nMAssay Description:The IC50 of each compound shown in Table was with respect to the kappa opioid receptor was determined. The cell line for the OPRK1 antagonist assay s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2026
Entry Details

LigandChemical structure of BindingDB Monomer ID 156544BDBM156544(US9682966, 326 | US10118915, Compound 326 | US2025...)
Affinity DataIC50: 1.90nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 156544BDBM156544(US9682966, 326 | US10118915, Compound 326 | US2025...)
Affinity DataIC50: 1.90nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent