BDBM157134 US9023767, Compound E

SMILES CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O

InChI Key InChIKey=JNGZXGGOCLZBFB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 157134   

TargetGamma-secretase-activating protein(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM157134(US9023767, Compound E)
Affinity DataIC50: 1.20nMAssay Description:Among the advantages of this Abeta 42 HTRF gamma-secretase assay is the construction of the biotinylated, recombinant CT6-I45F substrate, which has p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent