BDBM15778 6-(2-phenylethyl)pyridin-2-amine::6-Substituted 2-Aminopyridine 2

SMILES Nc1cccc(CCc2ccccc2)n1

InChI Key InChIKey=YEFODTWJWGCYRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15778   

TargetBeta-secretase 1(Human)
Astex

LigandPNGBDBM15778(6-(2-phenylethyl)pyridin-2-amine | 6-Substituted 2...)
Affinity DataIC50: 2.00E+6nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed