BDBM15784 3-N-{[3-(5-propoxypyridin-3-yl)phenyl]methyl}pyridine-2,3-diamine::3-Substituted 2-Aminopyridine 6c

SMILES CCCOc1cncc(c1)-c1cccc(CNc2cccnc2N)c1

InChI Key InChIKey=CXPQVRUSZWCUDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15784   

TargetBeta-secretase 1(Human)
Astex

LigandPNGBDBM15784(3-N-{[3-(5-propoxypyridin-3-yl)phenyl]methyl}pyrid...)
Affinity DataIC50: 2.40E+4nMpH: 5.0 T: 2°CAssay Description:Activity of BACE-1 was measured by monitoring the cleavage of its peptide substrate on a Fluoroskan Ascent plate reader with excitation and emission ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed