BDBM158178 US9029367, 2

SMILES COc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@]12COC[C@@]1(F)CSC(N)=N2

InChI Key InChIKey=JSYVKXRJYDRXHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 158178   

TargetBeta-secretase 1(Human)
Eli Lilly

US Patent
LigandPNGBDBM158178(US9029367, 2)
Affinity DataIC50: 13.2nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent