BDBM160640 US9045468, 56(+)::US9045468, 56(-)

SMILES Fc1ccc(cc1Cl)C12CCN(C1)Cc1cc(ccc21)-c1ccc(nn1)C(F)(F)F

InChI Key InChIKey=XBECXOYAIBURBV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 160640   

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160640(US9045468, 56(+) | US9045468, 56(-))
Affinity DataIC50:  2.40nMpH: 7.5 T: 4°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160640(US9045468, 56(+) | US9045468, 56(-))
Affinity DataIC50:  57.8nMpH: 7.5 T: 4°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160640(US9045468, 56(+) | US9045468, 56(-))
Affinity DataIC50:  799nMpH: 7.5 T: 4°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160640(US9045468, 56(+) | US9045468, 56(-))
Affinity DataIC50:  243nMpH: 7.9 T: 4°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160640(US9045468, 56(+) | US9045468, 56(-))
Affinity DataIC50:  78.6nMpH: 7.5 T: 4°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160640(US9045468, 56(+) | US9045468, 56(-))
Affinity DataIC50:  11.4nMpH: 7.9 T: 4°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In DepthDetails US Patent