BDBM160659 US9045498, 1

SMILES COc1cc(F)c(cc1C#N)C12CO[C@@H](COCc3ccccc3)C[C@H]1CSC(N)=N2

InChI Key InChIKey=MGERQPNRFSSESD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160659   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM160659(US9045498, 1)
Affinity DataIC50: 1.22E+3nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent