BDBM160670 US9045498, 12

SMILES Cn1cc(cn1)[C@H]1C[C@H]2CSC(N)=NC2(CO1)c1cc(ccc1F)C#N

InChI Key InChIKey=LQXAVXUZXAHPSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160670   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM160670(US9045498, 12)
Affinity DataIC50: 60nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent