BDBM160677 US9045498, 19

SMILES C[C@H]1C[C@H]2[C@@H](CF)SC(N)=N[C@]2(CO1)c1cc(CNCC(F)(F)F)ccc1F

InChI Key InChIKey=ZFLXFQVZVLHJPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160677   

TargetBeta-secretase 1(Human)
Pfizer

US Patent
LigandPNGBDBM160677(US9045498, 19)
Affinity DataIC50: 150nMAssay Description:Beta-secretase (BACE) is one of the enzymes involved in the generation of the amyloid beta peptide found in the amyloid plaques of Alzheimer's Diseas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent