BDBM160710 US9045500, 36

SMILES COC1CCC2(Cc3ccc(cc3C22N=C(N)c3cc(ccc23)C#N)C#CC2CC2)CC1

InChI Key InChIKey=XKZVEPQBIDYQBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160710   

TargetBeta-secretase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM160710(US9045500, 36)
Affinity DataIC50: 4.09nMpH: 4.4Assay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent