BDBM161744 US9051279, 21

SMILES COc1ccc(cc1)N1C(c2ccc(Cl)cc2)c2cc(OC)c(OCCN)cc2CC1=O

InChI Key InChIKey=SPROQMZYTFZBOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 161744   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 161744BDBM161744(US9051279, 21)
Affinity DataIC50: 2.53E+4nMAssay Description:The inhibition of p53-Hdm2 and p53-Hdm4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent