BDBM162381 US9051329, Example 6

SMILES CCN1C(=O)Cn2c1nc1nc(N3CCC[C@H](C3)NC(=O)OC(C)(C)C)n(Cc3cc(F)ccc3C#N)c1c2=O

InChI Key InChIKey=BKMVBDOZLBKNIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162381   

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162381(US9051329, Example 6)
Affinity DataIC50: 13.5nMpH: 7.5 T: 2°CAssay Description:DPP4 activity was measured using a continuous fluorometric assay. The substrate, Gly-Pro-AMC, was cleaved by DPP4 to release the fluorescent AMC grou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
US Patent