BDBM162878 US9056863, Example Ib1

SMILES Cc1cccc(Cl)c1-c1nnc2c(C)nc3cnccc3n12

InChI Key InChIKey=PVLTVWOFYFDBPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162878   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM162878(US9056863, Example Ib1)
Affinity DataIC50: 471nMpH: 7.6 T: 2°CAssay Description:A typical PDE2A assay was performed as follows: the assay was performed in 60 μL samples containing a fixed amount of the PDE2A enzyme (sufficie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
US Patent