BDBM163081 US9062026, Table III, Compound 9

SMILES COc1cccc2c(NCc3ccccc3)nc(nc12)-n1cnc2ccccc12

InChI Key InChIKey=ASENDNABGSGXNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163081   

TargetTransitional endoplasmic reticulum ATPase(Human)
Cleave Biosciences

US Patent
LigandPNGBDBM163081(US9062026, Table III, Compound 9)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:The ATPase assay is performed according the following protocol: Purified enzyme (20 nM p97), substrate (20 uM ATP) and a dose titration of compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
US Patent

TargetTransitional endoplasmic reticulum ATPase(Human)
Cleave Biosciences

US Patent
LigandPNGBDBM163081(US9062026, Table III, Compound 9)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed