BDBM163134 US9062026, Table III, Compound 62

SMILES Cc1cc2ccccc2n1-c1nc2CCCCc2c(NCc2ccccc2)n1

InChI Key InChIKey=VDNCBZCZOBNUHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163134   

TargetTransitional endoplasmic reticulum ATPase(Human)
Cleave Biosciences

Curated by ChEMBL
LigandPNGBDBM163134(US9062026, Table III, Compound 62)
Affinity DataIC50: 47nMAssay Description:Inhibition of human p97 ATPase incubated for 15 mins by ADP Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTransitional endoplasmic reticulum ATPase(Human)
Cleave Biosciences

Curated by ChEMBL
LigandPNGBDBM163134(US9062026, Table III, Compound 62)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:The ATPase assay is performed according the following protocol: Purified enzyme (20 nM p97), substrate (20 uM ATP) and a dose titration of compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
US Patent