BDBM163356 US9687479, 254 3-1-[(4-tert-butylphenyl)carbonyl]-5-[(5-chlorothiophen-2-yl)methyl]amino-1H-pyrazol-3-yl-1-methyl-1,2-dihydropyridin-2-one

SMILES Cn1cccc(-c2cc(NCc3ccc(Cl)s3)n(n2)C(=O)c2ccc(cc2)C(C)(C)C)c1=O

InChI Key InChIKey=CKMPLEJWDLOWKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163356   

TargetProthrombin(Human)
Verseon

US Patent
LigandPNGBDBM163356(US9687479, 254 3-1-[(4-tert-butylphenyl)carbonyl]-...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Human thrombin was obtained from Haematologic Technologies Inc. The chromogenic substrate S-2238 was obtained from DiaPharma. Thrombin was assayed in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent