BDBM163720 3-Cyclohexyl-5-{4-[4-(2-(methylthio)phenyl)piperazin-1-yl]butyl}-4,5-dihydro-1,2,4-triazin-6(1H)-one (19)
SMILES CSc1ccccc1N1CCN(CCCCC2NC(=NNC2=O)C2CCCCC2)CC1
InChI Key InChIKey=BVFNMWYWZSUBFG-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 163720
Affinity DataKi: 6nM ΔG°: -11.2kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to human 5-HT7 receptor extracted from HEK293 cell membrane assessed as inhibition of [3H]LSD binding to 5-HT7 by measuring inhibiti...More data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -10.7kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Binding affinity to human 5-HT1A receptor extracted from HEK293 cell membrane assessed as inhibition of [3H]-OH-DPAT binding to 5-HT1A by measuring i...More data for this Ligand-Target Pair