BDBM164237 US9688615, 48

SMILES CN(Cc1nc2cc(cc(c2[nH]1)C(F)(F)F)C(F)(F)F)C(=O)CNC(C)(C)C

InChI Key InChIKey=DCSDOGROVBLXKQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 164237   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164237(US9688615, 48)
Affinity DataIC50: 3.80E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164237(US9688615, 48)
Affinity DataIC50: 4.00E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164237(US9688615, 48)
Affinity DataIC50: 8.60E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164237(US9688615, 48)
Affinity DataIC50: 9.90E+3nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164237(US9688615, 48)
Affinity DataIC50: 1.00E+4nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164237(US9688615, 48)
Affinity DataIC50: 1.00E+4nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Degiacomo, Interim Trustee, Mark G.

US Patent
LigandPNGBDBM164237(US9688615, 48)
Affinity DataIC50: 1.00E+4nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent