BDBM165201 US8168651, Compound TABLE 14A.4::US9062043, Table 10, Compound 4

SMILES O=c1[nH]c2cc(-c3nnn[nH]3)ccc2c2ccccc12

InChI Key InChIKey=AKNIDSUYOQTONF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 165201   

TargetPoly [ADP-ribose] polymerase 1(Human)
Senhwa Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 165201BDBM165201(US9062043, Table 10, Compound 4 | US8168651, Compo...)
Affinity DataIC50: 30nMAssay Description:PARP assays are conducted using a chemiluminescent PARP assay kit (Trevigen). Briefly, reactions are performed in Histone-coated strip wells, by addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Senhwa Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 165201BDBM165201(US9062043, Table 10, Compound 4 | US8168651, Compo...)
Affinity DataIC50: 30nMAssay Description:PARP assays are conducted using a chemiluminescent PARP assay kit (Trevigen). Briefly, reactions are performed in Histone-coated strip wells, by addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cylene Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 165201BDBM165201(US9062043, Table 10, Compound 4 | US8168651, Compo...)
Affinity DataIC50: 2.00E+3nMAssay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cylene Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 165201BDBM165201(US9062043, Table 10, Compound 4 | US8168651, Compo...)
Affinity DataIC50: 2.00E+3nMpH: 7.2Assay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
US Patent