BDBM166696 5-phenyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto]-4-amino-1,2,4-triazole (6d)

SMILES Nn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1

InChI Key InChIKey=FEAYCHYBVPYGHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 166696   

TargetUncharacterized protein YOR062C(Baker's yeast)
Hunan University of Science and Technology

LigandPNGBDBM166696(5-phenyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...)
Affinity DataIC50: 7.45E+3nMpH: 6.8Assay Description:The synthesized compounds were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substrate. Mushroom ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details Article
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM166696(5-phenyl-3-[5-hydroxy-4-pyrone-2-yl-methylmercapto...)
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed