BDBM16677 Mixture of trans methyl(cyclopropylmethyl)diastereomers.::N-[(2S)-1-amino-3-phenylpropan-2-yl]-2-({[(1S,2S)-2-methylcyclopropyl]methyl}amino)-6-(N-methylmethanesulfonamido)pyridine-4-carboxamide::isonicotinamide, 16

SMILES C[C@H]1C[C@@H]1CNc1cc(cc(n1)N(C)S(C)(=O)=O)C(=O)N[C@H](CN)Cc1ccccc1

InChI Key InChIKey=YVDYUARNOWTGPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16677   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16677(N-[(2S)-1-amino-3-phenylpropan-2-yl]-2-({[(1S,2S)-...)
Affinity DataIC50: 34nMT: 2°CAssay Description:HEK293T cells were stably transfected with APP_NFEV. One day after plating, the cells were treated for 20-24 h with a medium containing a compound or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed