BDBM168025 US9073926, 59

SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2)c1

InChI Key InChIKey=GRKDQSJJVVIXFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168025   

TargetRibosomal protein S6 kinase alpha-3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM168025(US9073926, 59)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of RSK2 (unknown origin) preincubated for 1 hr followed by substrate addition and measured after 1 hr by luciferase analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM168025(US9073926, 59)
Affinity DataIC50: 0.200nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
US Patent