BDBM170126 4-(3-(4-Phenyl ethyl oxygen)-5-(2-hydroxyphenyl)-4, 5-dihydro pyrazole) benzene sulfonamide (4c)

SMILES CCOc1ccc(cc1)C1=NN(C(C1)c1ccccc1O)c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=BELCFXPRQIHBNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 170126   

Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170126(4-(3-(4-Phenyl ethyl oxygen)-5-(2-hydroxyphenyl)-4...)
Affinity DataIC50: 330nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170126(4-(3-(4-Phenyl ethyl oxygen)-5-(2-hydroxyphenyl)-4...)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant human MMP-2 incubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed