BDBM170439 US9085531, 21

SMILES CN1CC(c2cc3ccccc3s2)c2ccccc2C1

InChI Key InChIKey=OADBNBUTUOPDJD-UHFFFAOYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 170439   

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataKi:  8.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataKi:  11.5nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataKi:  14.3nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataKi:  28.4nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataIC50: 35nMAssay Description:Displacement of [3H]Citolapram from human SERT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataKi:  37.9nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataIC50: 38nMAssay Description:Displacement of [3H]WIN 35,428 from human DAT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataKi:  128nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170439(US9085531, 21)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]Nisoxetine from human NET expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed