BDBM170446 US9085531, 49

SMILES CN1CC(c2ccc3[nH]ccc3c2)c2ccccc2C1

InChI Key InChIKey=AAHLCKVWZXFMPB-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 170446   

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170446(US9085531, 49)
Affinity DataKi:  3.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170446(US9085531, 49)
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]WIN 35,428 from human DAT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170446(US9085531, 49)
Affinity DataKi:  5.80nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170446(US9085531, 49)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]Nisoxetine from human NET expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170446(US9085531, 49)
Affinity DataKi:  137nMpH: 7.4Assay Description:In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM170446(US9085531, 49)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]Citolapram from human SERT expressed in HEK293E cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed