BDBM172320 US9090589, 2

SMILES Nc1cccc(C[C@H]2CN(Cc3ccccc3)C[C@H]2NCCCc2ccccc2)n1

InChI Key InChIKey=HEIYXPDPUGXBFQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 172320   

TargetNitric oxide synthase, brain(Human)
Northwestern University

US Patent
LigandPNGBDBM172320(US9090589, 2)
Affinity DataKi:  4.80E+4nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent

TargetNitric oxide synthase, endothelial(Human)
Northwestern University

US Patent
LigandPNGBDBM172320(US9090589, 2)
Affinity DataKi:  1.22E+5nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent

TargetNitric oxide synthase, inducible(Human)
Northwestern University

US Patent
LigandPNGBDBM172320(US9090589, 2)
Affinity DataKi:  6.09E+5nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
US Patent