BDBM17251 ethyl 2-({[4-chloro-5-({4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}carbamoyl)thiophen-3-yl]methyl}(methyl)amino)acetate::thiophene-containing non-amidine inhibitor, 53

SMILES CCOC(=O)CN(C)Cc1csc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c1Cl

InChI Key InChIKey=UPQXHLVWWXCGHX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17251   

TargetCoagulation factor X(Human)
Berlex

LigandPNGBDBM17251(ethyl 2-({[4-chloro-5-({4-chloro-2-[(4-chloropheny...)
Affinity DataKi:  5.20nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Human)
Berlex

LigandPNGBDBM17251(ethyl 2-({[4-chloro-5-({4-chloro-2-[(4-chloropheny...)
Affinity DataKi:  2.30E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bovine)
Berlex

LigandPNGBDBM17251(ethyl 2-({[4-chloro-5-({4-chloro-2-[(4-chloropheny...)
Affinity DataKi: >5.00E+3nMAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed